Study of the proliferation in human gastric mucosa after in vivo bromodeoxyuridine labelling - 16 Downloads
Study of the proliferation in human gastric mucosa after in vivo bromodeoxyuridine labelling
S Patel, D A Rew, I Taylor, C S Potten, C Owen, S A Roberts
Abstract
Studies to measure human gastric crypt or gland cell proliferation may have a number of practical clinical applications in relation to both benign and malignant gastric conditions. Bromodeoxyuridine (BrdUrd) labels human gastric mucosal cells in the S phase. Computer aided data analysis of labelled mucosa allows static proliferative indices to be estimated, including the crypt labelling index (LI), the peak labelling position, the distribution of labelled cells and indirectly the crypt growth fraction.
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